Our new Obvious+ tissue clearing technique is the only approach that delipidates samples without transform in morphology and with negligible impact on structural integrity.
Megatome is really a vibrating microtome created to part a wide number of samples, from organoids and biopsy samples to expanded rodent brains and intact human organs. With high blade vibrating frequency and minimized blade deflection, Megatome enables large-throughput tissue sectioning with uniform floor profile, together with negligible tissue problems and knowledge decline.
Request a quote or demo Uniformly segment big tissues & sample arrays Megatome is the sole microtome that may segment samples as big as intact nonhuman primate and human organs, making it invaluable for fields like neuropathology.
Megatome is created for precision: the blade vibrates at a better frequency and bigger amplitude selection than other microtomes, and incorporates a exceptional deflection Command system.
SE makes use of a rotational electric field to disperse highly electromobile molecules (which include antibodies or surfactant micelles) all over a porous sample devoid of detrimental electrically charged structures within the tissue. This allows two-4 day clearing of intact organs,
Our preformulated EasyIndex Resolution raises and homogenize the refractive index of delipidated tissue samples, rendering them completely transparent. This enables light-weight penetration to the sample and guarantees the acquisition of high-resolution, in-aim impression info.
Megatome is really a novel microtome which allows for prime-precision sectioning of a wide range of tissue samples – from organoids, to arrays of animal organs, to intact human Mind hemispheres – with minimum tissue destruction and data loss.
eFLASH is often a fast tissue labeling system that permits for uniform full-organ staining in twenty rounds of labeling.
Absolutely delipidate entire mouse megatomi.com brains or comparably sized samples in only one day with SmartBatch+, or in a single week with our passive clearing kit.
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Leverage the Obvious+ tissue clearing process, together with eFLASH and patented stochastic electrotransport technologies, to speedily apparent and label whole organs. Important highlights and functions include things like:
Our novel Protect tissue preservation technique types intramolecular bonds making use of polyfunctional, versatile epoxides to stabilize tissue architecture and safeguard the sample’s endogenous fluorescence, protein antigenicity and nucleic acids.